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OCR: estosteroneln normal men, the production rates of me, and the adrenal androgen, androstenedi and the average some 5 and 3mg/d, respectively ol average production rates of oestrone and oestrad y (Fig. approximately 66 and 45ug/d, respective 11.9a). All of the oestrone is formed fron tof circulating precursors; thirty-five per cer osterone, oestradiol is derived from circulating te er cent is fifty per cent from oestrone, and fifteen hin levels secreted by the testes. When gonadotrop estis are elevated, oestradiol secretion by the increase